The secret weapon in the skin healing and anti-aging war is Vitamin B3.

Scientists have known about the skin benefits of ingesting Vitamin B3 for ages, but Dr Spiller skin care experts have now uncovered an exciting new advancement in vitamin -enriched cosmetics: Niacinamide, the physiologically active form of Vitamin B3.  And Vitamin B3 has a potentially powerfully anti-ageing effect on the skin when applied topically.

This potent ingredient has been incorporated into the Dr Spiller Vitamin C-Plus Serum.  Vitamin C in this serum has been stabilised with Dr Spiller’s magnesium and glycol technology stabilising Vitamin C and ensuring potency and efficacy.

The Vitamin C-Plus Serum’s exceptional anti-ageing formulation of Vitamin A, C, B3, B9, B12 and Retinol is scientifically proven to nurture collagen and elastin production for a more radiant and uniform skin tone.

Vitamins A, B3, B9, B12 and C are essential vitamins not produced by the human body and can only be obtained via diet and topical application.

Let’s look at these vitamins individually. 

Vitamin C is a potent antioxidant that nurtures natural collagen synthesis for a more supple appearance.

Retinol – an active derivative of Vitamin A that renews the appearance of the skin.  It is also an effective antioxidant that boosts the activity of vitamins C and E.

Niacinamide (Vitamin B3) Visibly brightens the skin for a revitalised appearance

Cyanocobalamin(Vitamin B12) a potent antioxidant

Folic Acid (Vitamin B9) Nurtures the skin for a younger appearance.

Vitamin E: A skin-identical potent antioxidant, naturally secreted by the sebaceous glands for environmental moisture protection.

Panthenol (Pro -Vitamin B5) is present in all living cells. Readily absorbed and penetrates deeply. Intensely hydrating, has powerful anti-inflammatory properties.  Deficiency of Vitamin B5 can lead to dermatological disorders.

Evening Primrose oil: A plant oil rich in biomimetic fatty acids and gamma-linolenic acid.

 Clinical Trials 

Clinical trial results have indicated that Niacinamide actually increases the turnover of the stratum corneum layer and thus helps to make the skin more resistant to environmental damage.  As well as improving skin barrier function, research has shown that topical treatments containing Niacinamide can:

  • visibly reduce hyperpigmentation
  • stimulate collagen synthesis
  • reduce sebum production
  • and decrease pore size.


As you can see the Niacinamide incorporated in this Vitamin C Plus Serum is incredibly useful for all skin types as it not only fights ageing but also other common skin concerns.  It does this by penetrating the dermis layer of the skin stimulating the vasodilation of the blood vessels and increasing blood flow and accelerating the removal of toxins trapped in the skin.

At Dermal Essence, we now incorporate the Niacinamide in our collagen fleece mask activator to strengthen the barrier function of the skin.